Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp140 | Cell biology: osteoblasts and bone formation | ECTS2014

Release kinetic of prolyl hydroxylase inhibitors from collagen barrier membranes in vitro

Hamid Omar , Pensch Manuela , Agis Hermann

Collagen barrier membranes are used in guided tissue regeneration to support bone healing and periodontal regeneration. Pharmacological inhibitors of prolyl-hydroxylases (PHD) can support hard and soft tissue regeneration and are therefore a promising tool for periodontal therapy. Here we evaluate the release kinetic of the PHD inhibitors dimethyloxaloylglycine and L-mimosine from the collagen barrier membranes.The PHD inhibitors were lyophilized onto co...

ba0005p145 | Cell biology: osteoblasts and bone formation | ECTS2016

Evaluation of release kinetics and mitogenic capacity of collagen barrier membranes supplemented with the secretome of activated platelets

Mozgan Eva-Maria , Edelmayer Michael , Janjić Klara , Pensch Manuela , Fischer Michael , Agis Hermann

Success in periodontal regeneration through guided tissue regeneration relies on the healing capacity of the host tissue. Platelet preparations are mitogenic and stimulate regeneration through high growth factor levels. Here we assessed collagen barrier membranes (CBM) as carriers for the secretome of activated platelets. We evaluated cell-attachment, the release of the secretome, and cell proliferation.Secretome of washed platelets (washed PSEC) and unw...