Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p66 | (1) | ICCBH2019

Bone densitometry and body composition in children with hypophosphatasia

Mciver William , Whittaker Lucy , Crabtree Nicola , Hogler Wolfgang , Saraff Vrinda

Hypophosphatasia (HPP) is a rare genetic disease characterised by low tissue-nonspecific alkaline phosphatase activity, causing defective mineralisation of bone and teeth. There is limited data on the measurement of bone mineral density (BMD) and body composition in these children.Objectives: To assess whether BMD and lean body mass (LBM) in treatment naïve children with HPP correlate with functional outcomes using the 6-minute walk test (6MWT)....