Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp14 | Arthritis and other joint diseases: translational and clinical | ECTS2013

Prophylaxis of gout flare with colchicine and vitamin C

Monov Simeon , Monova Daniela , Rashkov Rasho

Background: The incidence and prevalence of gout have markedly increased over the last few decades in keeping with the rise in prevalence of obesity and metabolic syndrome. The management of gout in patients with associated metabolic syndrome and comorbid illnesses such as renal impairment was difficult because of limited treatment options. Recent efficacy and safety data favour lower over higher doses of colchicine, and oral corticosteroids over non-steroidal anti-inflammator...

ba0003pp393 | Other diseases of bone and mineral metabolism | ECTS2014

Adult Niemann–Pick disease type B with myositis ossificans: a case report

Shumnalieva Russka , Monov Simeon , Shoumnalieva-Ivanova Viara , Rashkov Rasho , Stoilov Rumen

Introduction: Niemann–Pick disease (NPD) is a rare autosomal recessive lysosomal lipid storage disorder. It is caused by mutations of genes which products are involved in the metabolism of sphingolipids. Their dysfunction causes sphingomyelin to accumulate in different organs which leads to progressive multisystemic disorder. Types A and B NPD are caused by mutations in sphingomyelin phosphodiesterase-1 gene with deficiency of acid sphingomyelinase (ASM). Types C and D NP...

ba0005p289 | Osteoporosis: evaluation and imaging | ECTS2016

Sleep apnea and bone mineral density

Monova Daniela , Monov Simeon , Stambolova Maria , Peneva Evgenya , Shumnalieva Ruska , Sichanova Ljuboslava

Introduction: Obstructive sleep apnea (OSA) is a common sleep-related respiratory disorder characterized by repeated episodes of apnea and hypopnea resulting in sleep fragmentation, nocturnal hypoxia and hypercapnia, and excessive daytime sleepiness. OSA has recently become a well-recognized problem in view of its high prevalence in the general population. OSA is associated with many endocrine disorders (hypogonadotropic hypogonadism, hypercortisolism, glucose intolerance). Th...