Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p126 | (1) | ICCBH2019

Anemia - novel clinically significant finding during intravenous pamidronate therapy of children diagnosed with osteogenesis imperfecta

Michalus Izabela , Nowicka Zuzanna , Pietras Wiktoria , Nowicka Maja , Byrwa Agnieszka , Albińska Paulina , Jakubowska-Pietkiewicz Elzbieta

Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by fragile bones susceptible to fractures. No definite cure for OI exists. Bisphosphonates, although not implicitly recommended in children due to deficient efficacy and safety data, have been administered off-label to OI patients for over 20 years. Short-term adverse effects of intravenously administered bisphosphonates are generally mild. Although anemia is a known side effect of bisphosphonates in adults,...