Searchable abstracts of presentations at key conferences on calcified tissues

ba0004is4 | (1) (1) | ICCBH2015

Vertebral fracture assessment

Offiah Amaka C

Osteoporotic fractures of the vertebrae are often silent and if left untreated will lead to progressive loss of vertebral body height and significant kyphoscoliosis, with its associated morbidity. However if vertebral fractures (VF) are detected early, treatment with bisphosphonates accelerates healing of prevalent fractures and reduces incident fractures.A survey of members of the British Paediatric and Adolescent Bone Group showed that treatment is sta...

ba0004is4biog | (1) (1) | ICCBH2015

Vertebral fracture assessment

Offiah Amaka C

Biographical DetailsAmaka C Offiah is Senior Lecturer and Consultant Paediatric Radiologist at the University of Sheffield and Sheffield ChildrenÂ’s Hospital. She has a specialist interest in the musculoskeletal system. She has co-authored two books, seven book chapters, published 67 peer-reviewed articles and given over 100 invited national and international lectures. She is Convenor...

ba0006p082 | (1) | ICCBH2017

Impact of age, sex, location of injury, physical activity, vitamin D and calcium intake on the injury outcome of wrist and ankle in children

Alshamrani Hassan A , Alloub Hana , Burke Derek , Offiah Amaka C

Objectives: The aim of this study was to assess the impact of age, sex, location of injury, physical activity, dietary intake of calcium and vitamin D on injury outcome in otherwise healthy children.Materials: This study was a cross-sectional prospective study. Children aged 6 to 15 years who presented to the Emergency Department of a single tertiary paediatric referral hospital were recruited. Children were included it they were known not to have underl...

ba0007p88 | (1) | ICCBH2019

Diagnostic performance of morphometric vertebral fracture analysis (MXA) in children using a 33-point software programme

Alqahtani Fawaz , Crabtree Nicola , Bromiley Paul , Cootes Timothy , Broadley Penny , Lang Isla , Offiah Amaka C

Background: There is significant inter and intraobserver variability in diagnosing vertebral fractures in children. We aimed to evaluate the diagnostic accuracy of morphometric vertebral fracture analysis (MXA) using a 33-point software programme designed for adults, on dual-energy x-ray absorptiometry (DXA) images of children.Methods: Lateral spine DXA images of 420 children aged between 5 and 18 years were retrospectively reviewed. Vertebral fracture a...

ba0006p037 | (1) | ICCBH2017

Early fragility fractures in Zellweger syndrome spectrum – peroxisome dysfunction affecting osteogenesis?

Nicholls Rachel , Pierre Germaine , Chronopoulou Effie , Smithson Sarah F , Offiah Amaka C , Barton John S , Burren Christine P

Background: Peroxisomal Biogenesis Disorders (PBD) is a group of rare metabolic diseases in which peroxisomal function is disrupted. PBD encompasses Zellweger Syndrome Spectrum (ZSS) disorders, which range in severity from classical ZS with severe neurological impairment and markedly reduced life expectancy to Refsum Disease presenting later in childhood. Recent fragility fractures in our ZSS patients in very early childhood prompted case series review.P...

ba0006p042 | (1) | ICCBH2017

Osteogenesis imperfecta type VI presenting as suspected physical abuse -- a report of two cases

Sithambaram Sivagamy , Bishop Nick , Shankar Lata , Offiah Amaka C , Pollitt Rebecca C , Balasubramanian Meena , Saggar Anand K , Arundel Paul

Background: Osteogenesis imperfecta (OI) type VI is a rare recessive disease that may present with long bone fractures in early childhood. Bone in this condition is particularly brittle; the resulting pattern of long bone fractures and lack of distinct radiographic findings can make the diagnosis less obvious than in other types of OI. We report 2 unrelated children who presented with long bone fractures and were suspected of having suffered physical abuse with removal of pare...