Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp257 | Osteoporosis: pathophysiology and epidemiology | ECTS2014

Molecular evidence of osteoblast dysfunction in elderly men with osteoporotic hip fractures

Foger-Samwald Ursula , Afarin Alaghebandan , Patsch Janina , Schamall Doris , Salem Sylvia , Mousavi Mehdi , Pietschmann Peter

Fractures of the hip are serious complications associated with osteoporosis. In previous work we found evidence of osteoblast dysfunction in middle aged men with idiopathic osteoporosis. The aim of this study was to investigate gene expression and bone microarchitecture in bone samples derived from elderly men with osteoporotic hip fractures. Femoral heads and adjacent bone tissue from 12 men with low-trauma hip fractures (mean age 82±7 years) and consecutive surgical hip...

ba0007p79 | (1) | ICCBH2019

Novel imaging approaches to the quantification of musculoskeletal alterations in X-linked hypophosphatemic rickets (XLH)

Raimann Adalbert , Mehany Sarah N , Feil Patricia , Weber Michael , Boni-Mikats Andrea , Klepochova Radka , Krssak Martin , Pietschmann Peter , Haeusler Gabriele , Schneider Johannes , Raum Kay , Patsch Janina

Objectives: X-linked hypophosphatemia (XLH) is a rare genetic disorder of phosphate metabolism caused by mutations in the PHEX gene. This pilot study aims to apply novel imaging techniques to asses the musculoskeletal phenotype of XLH patients by bidirectional axial transmission (BDAT) ultrasound, magnetic resonance spectroscopy (MRS) and high resolution peripheral quantitative computed tomography (HR-pQCT).Methods: BDAT bone ultrasound of the radius and...