Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp99 | Cancer and bone: basic, translational and clinical | ECTS2014

Changes in bone mineral density and biochemical markers of bone turnover in postmenopausal women with breast cancer initiating aromatase inhibitors therapy

Luchavova Maria , Zimovjanova Martina , Zikan Vit , Pribylova Jana , Cabinakova Michaela , Petruzelka Lubos

Postmenopausal women with early stage hormone-receptor-positive breast cancer (EBC) are standardly treated with aromatase inhibitors (AIs). However, one side-effect of AIs treatment is a decrease in bone mineral density (BMD) and an increased risk of fracture. The objectives of this study were to examine: i) changes in bone formation (N-terminal propeptide of type I procollagen; PINP) and bone resorption (cross-linked C-telopeptides of bone type I collagen; CTX) markers, as we...

ba0003pp280 | Osteoporosis: pathophysiology and epidemiology | ECTS2014

Bone health in patients with type 2 diabetes mellitus

Raska Ivan , Raskova Maria , Michalska Dana , Soupal Jan , Skrha Jan , Zikan Vit

Patients with type 2 diabetes (T2DM) have an increased risk of hip and vertebral fractures compared to non-T2DM subjects. The bone mineral density (BMD) does not reflect the impaired bone quality in T2DM patients. The aim of the present study was to investigate the relationship between BMD and bone formation (N-terminal propeptide of type I procollagen, PINP; osteocalcin, OC) and bone resorption (cross-linked C-telopeptides of bone type I collagen, CTX) markers, as well as cha...