Bone Abstracts (2016) 5 P341 | DOI: 10.1530/boneabs.5.P341

Trend of incidence, mortality, and future projection of vertebral fracture in Korea using nationwide claims data

Young-Kyun Lee1, Tae-Young Kim2, Sunmee Jang3, Ha-Young Kim4, Deog-Yoon Kim5, Eun-Hee Cho6 & Yong-Chan Ha6


1Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; 2Department of Orthopaedic Surgery, School of Medicine, Hallym University, Anyang, Republic of Korea; 3College of Pharmacy, Gachon University, Incheon, Republic of Korea; 4Department of Internal Medicine, School of Medicine, Wonkwang University, Gunpo, Republic of Korea; 5Department of Nuclear Medicine, Kyung Hee University Medical Center, Seoul, Republic of Korea; 6Department of Orthopaedic Surgery, School of Medicine, Chung-Ang University, Seoul, Republic of Korea.


Introduction: Vertebral fracture has been recognized as a major health concern. Our purposes were to evaluate the trends in the incidence and mortality of vertebral fracture between 2008 and 2012 and predict the number of vertebral fracture that will occur in Korea up to 2025, using nationwide data from the National Health Insurance Service (NHIS).

Method: A nationwide data set was evaluated to identify all new visits to medical institutes for vertebral fracture in men and women aged 50 years or older between 2008 and 2012. The incidence, mortality rates and Estimates of the number of vertebral fracture were calculated using Poisson regression.

Result: The number of vertebral fractures increased over the time span studied. Men and women experienced 14,808 and 55,164 vertebral fractures in 2008 and 22,739 and 79,903 in 2012, respectively. This reflects an increase in the incidence of vertebral fracture for both genders (men, 245.3/100,000 in 2008 and 312.5/100,000 in 2012; women, 780.6/100,000 in 2008 and 953.4/100,000 in 2012). The cumulative mortality rate in the first year after vertebral fracture decreased from 8.51% (5955/69,972) in 2008 to 7.0% (7187/102,642) in 2012. The overall standardized mortality ratio (SMR) of vertebral fracture at 1 year post-fracture was higher in men (7.76, 95% CI: 7.63–7.89) than in women (4.70, 95% CI: 4.63–4.76). The total number of vertebral fractures is expected to reach 157,706 in 2025.

Conclusion: The incidence of vertebral fracture increased in Korea in the last 5 years, and the socioeconomic burden of vertebral fracture will continue to increase in the near future.

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