Searchable abstracts of presentations at key conferences on calcified tissues
Bone Abstracts (2013) 1 W1.2 | DOI: 10.1530/boneabs.1.W1.2

ECTS2013 Workshops Fat and bone (3 abstracts)

Anorexia nervosa and bone

Madhusmita Misra


Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.


Anorexia nervosa (AN) occurs in 0.2–1% of adolescent girls and is characterized by physiological and adaptive changes in the various endocrine axes. Changes also occur in many hormones secreted or regulated by fat (a reflection of energy stores) that can impact bone. The physiological changes observed in various endocrine axes in AN in turn cause impaired bone accrual rates, low bone density (associated with increased marrow fat) and impaired bone microarchitecture. This raises concerns regarding attainment of peak bone mass, an important determinant of bone health and fracture risk in later life. Weight and menses recovery are associated with some improvement in bone accrual, but residual deficits persist. Therapeutic strategies to improve bone accrual in AN are limited, and include physiologic estrogen replacement in adolescents, and use of bisphosphonates in adults.

Volume 1

European Calcified Tissue Society Congress 2013

Lisbon, Portugal
18 May 2013 - 22 May 2013

European Calcified Tissue Society 

Browse other volumes

Article tools

My recent searches

No recent searches.

My recently viewed abstracts

Authors