Searchable abstracts of presentations at key conferences on calcified tissues
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European Calcified Tissue Society Congress 2014

Prague, Czech Republic
17 May 2014 - 20 May 2014

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European Calcified Tissue Society Annual Congress, 17 - 20 May 2014; Prague, Czech Republic

Poster Presentations

Cell biology: osteocytes

ba0003pp174 | Cell biology: osteocytes | ECTS2014

Structural analysis of tooth and jawbone in a type 2 diabetes mouse model

Repp Felix , Kollmannsberger Philip , Roschger Andreas , Roschger Paul , Wagermaier Wolfgang , Fratzl Peter , Weinkamer Richard

In type 2 diabetes mellitus (T2DM) patients, an increased fracture risk is observed, although the bone mineral density is even higher than in non-diabetic patients. This raises the question of the quality of the organic and inorganic matrix in bone1–3. T2DM is also known to forward dysfunctions in the development of soft tissues such as brittle skin due to cross-linking of the collagen or inflammation of the gingiva. For the latter, a possible influence of diab...

ba0003pp175 | Cell biology: osteocytes | ECTS2014

Low estrogens, weak bones: unravelling estradiol remodelling effect in bone metabolic/lipid profiles

Silva Ana Maria , Moreira Ana Carolina , Santos Maria Sancha , Videira Romeu , Carvalho Rui , Sardao Vilma

Introduction: For the very first time were assessed in vivo the metabolic and lipid profiles of osteocytes. During menopause period the appearance of an osteoporotic condition can be associated with an overall metabolic decline in bone cells, as well an increase of reactive oxygen species (ROS), and we hypothesized that it is mainly attributed to osteocytes metabolic and lipid changes, which could be apparently attenuated after raising blood estradiol (E2) levels. To ...

ba0003pp176 | Cell biology: osteocytes | ECTS2014

Effects of osteocyte apoptosis and mechanical strain on osteoblast proliferation and migration

Ko Seong-Hee , Lee Hee Su , Baek Kyunghwa

There are several evidences that osteocyte plays a critical role in bone remodeling. Healthy or apoptotic osteocytes can send signals to other bone surface cells like osteoblasts, osteoclasts, osteoclast precursors and bone lining cells through their networking in canaliculi. Therefore, to determine the role for osteocytes in bone remodeling, we examined the effect of healthy and apoptotic osteocytes on osteoblasts proliferation and recruitment. In addition, the effects of mec...