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Bone Abstracts (2014) 3 PP243 | DOI: 10.1530/boneabs.3.PP243

Osteoporosis: evaluation and imaging

Trabecular bone score, bone mineral density and body composistion in men of different ages

Vladyslav Povoroznyuk1, Anna Musiienko1, Roksolana Povoroznyuk1, Nataliia Dzerovych1 & Didier Hans2

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1D.F. Chebotarev Institute of Gerontology NAMS Ukraine, Kyiv, Ukraine; 2Center of Bone diseases, Lausanne University Hospital, Lausanne, Switzerland.


The aim of this study was to evaluate the trabecular bone score (TBS), bone mineral density (BMD) and body composition in men of various ages.

Materials and methods: 300 men aged 40–87 years (mean age – 60.5±0.6 years; mean height – 1.61±0.003 m; mean weight – 84.1±0.9 kg) were examined. The patients were divided into the following age-dependent groups: 40–49 years (n=52), 50–59 years (n=90), 60–69 years (n=88), 70–79 years (n=58), 80–87 years (n=12). The BMD of total body, PA lumbar spine and proximal femur were measured by the DXA method (Prodigy, GEHC Lunar, Madison, WI, USA) and PA spine TBS were assessed by the TBS iNsight software package installed on our DXA machine (Med-Imaps, Pessac, France).

Results: We observed a significant decrease of TBS (L1–L4) as a function of age (40–49 years – 1.161±0.022; 50–59 years – 1.108±0.018; 60–69 years – 1.114±0.016; 70–79 years – 1.061±0.024; 80–87 years – 1.105±0.049; F=2.49; P=0.04). We also found the decrease of BMD of lumbar spine (40–49 years – 1.186±0.003 g/cm2; 50–59 years – 1.128±0.021 g/cm2; 60–69 years – 1.224±0.026 g/cm2; 70–79 years – 1.247±0.034 g/cm2; 80–87 years – 1.131±0.064 g/cm2; F=3.25; P=0.01) and proximal femur (40–49 years – 1.050±0.021 g/cm2; 50–59 years – 0.996±0.018 g/cm2; 60–69 years – 1.032±0.018 g/cm2; 70–79 years – 1.004±0.021 g/cm2; 80–87 years – 0.879±0.050 g/cm2; F=3.34; P=0.01) with age.

Significant correlation was observed between TBS and BMD of lumbar spine (TBS=1.017+0.079×BMD (L1–L4); r=0.11; t=1.90; P<0.05) and lean (TBS=1.441−0.000006×Lean mass (g); r=−0.25; t=−4.50; P=0.00001) and fat (TBS=1.33−0.000009×Fat mass (g); r=−0.54; t=−11.04; P<0.001) masses.

Conclusion: TBS and BMD in examined men significantly decreased with ageing. We have also found a significant correlation of TBS and BMD of lumbar spine, lean and fat masses.

Volume 3

European Calcified Tissue Society Congress 2014

Prague, Czech Republic
17 May 2014 - 20 May 2014

European Calcified Tissue Society 

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