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Bone Abstracts (2014) 3 PP244 | DOI: 10.1530/boneabs.3.PP244

Osteoporosis: evaluation and imaging

Trabecular bone score, bone mineral density and body composistion in women of different ages

Vladyslav Povoroznyuk1, Nataliia Dzerovych1, Roksolana Povoroznyuk1, Anna Musiienko1 & Didier Hans2


1D.F. Chebotarev Institute of gerontology NAMS Ukraine, Kyiv, Ukraine; 2Center of Bone diseases, Lausanne University Hospital, Lausanne, Ukraine.

The aim of this study was to evaluate the trabecular bone score (TBS), bone mineral density (BMD) and body composition in women of various ages.

Materials and methods: 494 women aged 41–89 years (mean age, 63.6±0.4 years; mean height, 1.61±0.003 m; and mean weight, 74.0±0.6 kg) were examined. The patients were divided into the following age-dependent groups: 40–49 years (n=35), 50–59 years (n=130), 60–69 years (n=177), 70–79 years (n=128), and 80–88 years (n=24). BMD of total body, PA lumbar spine and proximal femur were measured by the DXA method (Prodigy, GEHC Lunar, Madison, WI, USA) and PA spine TBS were assessed by the TBS iNsight Software package installed on our DXA machine (Med-Imaps, Pessac, France).

Results: We observed a significant decrease of TBS (L1–L4) as a function of age (40–49 years, 1.321±0.021; 50–59 years, 1.245±0.012; 60–69 years, 1.189±0.011; 70–79 years, 1.166±0.001; and 80–88 years, 1.114±0.033; F=14.28; P<0.001). We also found the lumbar spine BMD (40–49 years, 1.156±0.038 g/cm2; 50–59 years, 1.068±0.018 g/cm2; 60–69 years, 1.022±0.016 g/cm2; 70–79 years, 1.003±0.001 g/cm2; and 80–89 years, 1.007±0.037 g/cm2; F=5.11; P=0.0005) and proximal femur BMD (40–49 years, 1.012±0.037 g/cm2; 50–59 years, 0.940±0.013 g/cm2; 60–69 years, 0.923±0.011 g/cm2; 70–79 years, 0.843±0.012 g/cm2; and 80–89 years, 0.741±0.020 g/cm2; F=20.09; P<0.001) decrease with age.

Significant correlation was observed between TBS and BMD of lumbar spine (TBS=0.93+0.26×BMD (L1–L4); r=0.37; t=8.61; P<0.001), proximal femur (TBS=0.97+0.27×BMD (L1–L4); r=0.29; t=6.61; P<0.001) and lean (TBS=1.34−0.000003×lean mass (g); r=−0.11; t=−2.47; P=0.01) and fat (TBS=1.25−0.000003×fat mass (g); r=−0.100; t=−2.200; P=0.03) masses.

Conclusion: TBS and BMD of the examined women significantly decreased with ageing. We have also found a significant correlation of TBS and BMD of lumbar spine and proximal femur, lean and fat masses.

Volume 3

European Calcified Tissue Society Congress 2014

Prague, Czech Republic
17 May 2014 - 20 May 2014

European Calcified Tissue Society 

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