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Bone Abstracts (2014) 3 PP276 | DOI: 10.1530/boneabs.3.PP276

Osteoporosis: pathophysiology and epidemiology

Is it necessary to consider fracture site in osteoporosis?

Kwangkyoun Kim


Konyang University Hospital, Daejeon, Republic of Korea.

Objectives: To compare the incidence of osteoporosis and the related factors among fracture sites in above 50-year-old patients with fractures caused by low-energy trauma.

Materials and methods: 714 patients with fracture from low energy trauma were evaluated retrospectively. By the dual-energy X-ray absorptiometry, we measured bone mineral density BMD at lumbar spine and proximal femur, and compared the incidence of osteoporosis, age, sex, BMI, previous fracture history, past osteoporosis medication history according to each fracture sites.

Results: BMD was decreased according to increasing age with statistical significance (P<0.001). Sex has no significant difference according to fracture site (P=0.141). Average age of patients with osteoporotic fracture was 73.8, 72.8, 66.3, 73.4, 78.3 years old according to fracture site as T-spine, L-spine, distal radius, proximal humerus and proximal femur, respectively. There was significant difference among groups (P<0.001). Average BMI related with osteoporotic fracture site was 22.9, 22.7, 23.4, 23.0, 21.7 kg/m2, respectively and it showed significant difference among groups (P<0.001). Average BMD (T-score) related with osteoporotic fracture site was 0.587 g/cm2 (−3.5), 0.614 g/cm2 (−3.1), 0.647 g/cm2 (−2.6), 0.597 g/cm2 (−3.1), 0.554 g/cm2 (−3.5), with significant difference among groups (P<0.001). Previous fracture history had no significant difference among groups (P=0.078). Previous osteoporosis medication history had significant difference among the groups (P<0.001).

Conclusions: In conclusion, consideration of fracture site may be necessary for prevention and treatment of osteoporosis.

Volume 3

European Calcified Tissue Society Congress 2014

Prague, Czech Republic
17 May 2014 - 20 May 2014

European Calcified Tissue Society 

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