ICCBH2015 Poster Presentations (1) (201 abstracts)
Chronic recurrent multifocal osteomyelitis: the value of whole-body MRI in a series of 34 children
Benjamin Jacobs , Mathew Brown , Ananya Guha , Dion Alexandrou , Paul O’Donnell & Richard Keen
Royal National Orthopaedic Hospital, Stanmore, London, UK.
Objectives: To assess the role of whole-body MRI in the diagnosis and management of chronic recurrent multifocal osteomyelitis (CRMO) is a benign and non-infective auto-inflammatory bone disorder characterised by multiple and recurrent inflammatory bone lesions. No universal diagnostic criteria exist.
Methods: Retrospective review of CRMO cases diagnosed at this hospital between 2008 and 2014. Cases were identified from patient records and clinical information was collated from radiology and histopathology records and individual case notes.
Results: Forty-seven CRMO cases were identified who had had whole-body MRI, of these 34 cases were children. The number of whole-body MRI scans per case ranged from 1 to 5. Whole-body MRI identified multifocal lesions were found most frequently in the clavicle, tibia and femur. All cases were managed with non-steroidal anti-inflammatory and/or bisphosphonate medication. No cases received steroid or anti-TNF treatment.
Conclusion: In the absence of specific diagnostic criteria, whole-body MRI in combination with clinical assessment can make the diagnosis of CRMO. Whole-body MRI has almost entirely replaced biopsy in the diagnosis of CRMO at our institution.
Disclosure: The authors declared no competing interests.
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