Searchable abstracts of presentations at key conferences on calcified tissues
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43rd Annual European Calcified Tissue Society Congress

Rome, Italy
14 May 2016 - 17 May 2016

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Poster Presentations

Preclinical and ex vivo imaging

ba0005p485 | Preclinical and ex vivo imaging | ECTS2016

Sex-related differences of morphological and densitometric properties of mandible in silver foxes (Vulpes vulpes)

Luszczewska-Sierakowska Iwona , Tatara Marcin , Krupski Witold , Charuta Anna , Tymczyna Barbara , Furmanek Miroslaw , Maciejewski Ryszard

The aim of this study was to determine morphological and densitometric parameters of mandible obtained from male and female silver foxes (Vulpes vulpes). The study was performed on 1-year-old males (n=7) and females (n=8). Mandible was isolated and subjected to morphological and densitometric analysis using quantitative computed tomography (QCT) method and Somatom Emotion Siemens apparatus (Siemens, Erlangen, Germany) equipped with Somaris/5 VB10B so...

ba0005p486 | Preclinical and ex vivo imaging | ECTS2016

Age-related changes in 3D bone microstructure are more pronounced in the sub-endplate region than in the central region of human vertebral bodies

Thomsen Jesper Skovhus , Ebbesen Ebbe Nils , Bruel Annemarie

The vertebral body microstructure of young individuals appears to be divided into three equally high horizontal regions: two adjacent to the endplates and one in the centre of the vertebral body. With age this subdivision of the vertebral microstructure seems to vanish. The aim of the study was to investigate the differences in the age-related changes in vertebral microstructure in the two regions.Vertebral (L2) bone specimens from 41 women and 39 men ag...

ba0005p487 | Preclinical and ex vivo imaging | ECTS2016

The CAM assay for human bone regeneration evaluation: the potential of Laponite® clay gel for growth factor delivery ex vivo

Moreno-Jimenez Ines , Hulsart-Billstrom Gry , Lanham Stuart A , Kanczler Janos M , Evans Nicholas D , Oreffo Richard O C

An increasing number of biomaterials are in development, seeking to mimic the natural cascade of events during fracture repair. However, these biomaterials need to be rigorously tested prior to clinical application. In vitro testing lacks the physiological environment, while in vivo studies do not always predict the patient response. Here we hypothesize that the chorioallantoic membrane (CAM) assay can be used to culture human living bone and we aim to examin...

ba0005p488 | Preclinical and ex vivo imaging | ECTS2016

Mandibular bone: an unusual trabecular bone?

Coutel Xavier , Olejnik Cecile , Marchandise Pierre , Chauveau Christophe , Penel Guillaume

Introduction: Mandibular alveolar bone appears to be particularly sensitive to local factors compared to other skeletal sites. In growing rats, occlusal hypofunction leads to a dramatic decrease of the alveolar bone microarchitecture. Intra-radicular bone surrounding teeth is a specific functional area with a high bone turnover. We hypothesized that the mechanical loading of the alveolar process during mastication may play a role in the preservation of the alveolar bone microa...

ba0005p489 | Preclinical and ex vivo imaging | ECTS2016

Quantitative assessment of radial bone structural distribution in the proximity of degradable implants by micro-computed tomography

Damm Timo , Barkmann Reinhard , Galli Silvia , Willumeit-Romer Regine , Gluer Claus-Christian

Degradable bone implants may provide improved long-term healing, tissue remodeling and quality of life. In order to optimize alloy composition and degradation properties, in-vivo monitoring of the degradation process and its impact on bone formation is essential because degradation progresses differently in-vivo versus in-vitro. We aim to understand how degradation of magnesium alloy implants influences bone remodeling and bone structure using Micro-...