Bone Abstracts

Aim: The aim of the research is to define the bone mineral density in patients, with Parkinson’s disease.

Methods: We examined 12 women with Parkinson’s disease and 12 healthy women of appropriate age (average age: −63.6±6.25 vs 62.2±6.83 years, P=0.5). The duration of Parkinson’s disease was at list 5 years. All patients reseived levodopa.

Results: BMD of women with Parkinson’s disease was significantly lower compared with BMD of women of control group on the level of total body (T-score =−1.86±1.32 vs −0.71±1.48, P<0.05, Z-score =−0.35±0.93 vs 0.51±1.05, P<0.05), lumbar spine (T-score =−1.56±1.22 vs 0.10±1.63, P<0.05, Z-score =−0.66±0.87 vs 0.72±1.53, P<0.05) and at the distal forearm (T-score =−1.87±1.32 vs 0.71±1.47, P<0.05, Z-score =−0.51±1.05 vs 0.38±1.22, P<0.05). Hip BMD was not different from control group. It is important to note that one woman with Parkinson’s disease has two hip endoprostheses after femoral neck fractures.

Conclusion: BMD in women with Parkinson’s disease is significantly lower than in healthy wowen of the same age.