Searchable abstracts of presentations at key conferences on calcified tissues

ba0004p109 | (1) | ICCBH2015

Effects of inorganic phosphate and FGF23 on C2C12 myoblast cells

Raimann Adalbert , Dangl Alexander , Sagmeister Susanne , Greber-Platzer Susanne , Haeusler Gabriele

Objectives: Dysregulation of systemic phosphate homeostasis is often associated with impairment of musculoskeletal tissue function. Many factors such as calcium levels and dysegulated endocrine mechanisms are thought to contribute. Inorganic phosphate and FGF23 have been shown to act via similar signaling pathways in several cell types but we are not aware of any detailed investigations into their effect on the differentiation and viability of skeletal muscle cells. W...

ba0007p219 | (1) | ICCBH2019

Comparison of cell separation methods, using relative expression of specific growth plate zone markers in a pig model

Javanmardi Alireza , Raimann Adalbert , Egerbacher Monika , Sagmeister Susanne , Gleiss Andreas , Haeusler Gabriele

Objective: Linear growth is achieved by enchondral ossification in epiphyseal growth plates (GP) of long bones. These highly organized cartilaginous tissues contain chondrocytes of all differentiational stages classified in 3–5 specific zones. Due to their discrete characteristics, distinct analysis of each zone is essential in basic GP research. While the efficiency of zonal separation is therefore highly influencing on study results, comparative data on commonly used me...