Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp116 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2013

Effect of high doses of vitamin D on arterial properties, adiponectin, leptin, and glucose homeostasis in type 2 diabetic patients

Shargorodsky Marina

Background and aims: Vitamin D supplementation has the potential to alleviate the cardiovascular damage in diabetic patients. The present study was designed to evaluate long term impact of high doses of vitamin D on arterial properties, glucose homeostasis, adiponectin and leptin in patients with type 2 diabetes mellitus.Methods and results: In randomized, placebo-controlled study 47 diabetic patients were assigned into two groups: Group 1 received oral ...

ba0005p2 | Arthritis and other joint diseases: translational and clinical | ECTS2016

Does adiponectin in serum or synovial fluid predict arthroscopy assessed cartilage damage severity in patients with symptomatic knee osteoarthritis?

Marina Shargorodsky

Background: Osteoarthritis (OA), the prevalent joint-affecting disease characterized by cartilage damage, is the leading cause of disability in adults and contributes to the excess of morbidity and healthcare costs. We performed the current trial to evaluate biomarkers, specifically adiponectin in serum and synovial fluid, associated with cartilage damage severity assessed by arthroscopy, in patients with symptomatic knee osteoarthritis.Methods: The 40 s...

ba0005p332 | Osteoporosis: pathophysiology and epidemiology | ECTS2016

Elevated body iron stores and circulating osteoprotegerin as independent predictors of hip fracture in postmenopausal women admitted for fragility fracture: time for new screening strategies?

Shargorodsky Marina

Background: Identification of risk factors may help us to understand the pathogenesis of osteoporotic hip fracture as well as to formulate development of better diagnostic, prevention and treatment strategies. The present study was designed to determine the impact of multiple metabolic risk factors such as markers of systemic inflammation (C-reactive protein), body iron stores (ferritin), insulin resistance (HOMA-IR) and bone remodeling (osteoprotegerin), for the prediction of...